ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0015.10-3 | Aetiology and heterogeneity of type 1 diabetes | ESPEYB15

10.3 Frequency and phenotype of T1DM in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank

NJ Thomas , SE Jones , MN Weedon , BM Shields , RA Oram , AT Hattersley

To read the full abstract: Lancet Diabetes Endocrinol. 2018;6:122-129T1DM formerly called juvenile or insulin dependent diabetes has so far been considered to be a disease of children adolescents and young adults according to traditional teaching. LADA or late autoimmune diabetes of the adult is known since several decades, however the older the patient with new onset diabetes the more li...
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ey0017.2-8 | Neonatal Diabetes Mellitus | ESPEYB17

2.8. Patterns of post-meal insulin secretion in individuals with sulfonylurea-treated KCNJ11 neonatal diabetes show predominance of non-KATP-channel pathways

P Bowman , TJ McDonald , BA Knight , SE Flanagan , M Leveridge , SR Spaull , BM Shields , S Hammersley , MH Shepherd , RC Andrews , KA Patel , AT Hattersley

To read the full abstract: BMJ Open Diabetes Research and Care2019; 7:e000721. PMID: 31908791Understanding of the molecular mechanisms underlying neonatal diabetes mellitus (NDM) has helped to transform the clinical management of some patients. Those with NDM due to mutations in the KCNJ11/ABCC8 genes can now be switched to oral sulphonylurea treatment and their daily insu...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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